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Modern cholesterol-lowering drugs act by inhibiting an enzyme (HMG-CoA reductase) needed for the formation of cholesterol in the liver. These HMG-CoA reductase inhibitors, called statins, are sold as Lipitor, Mevacor, Pravacol, Zocor, etc.

1. Weakness and Muscle Wasting: This is the most common side effect of statin drugs, occurring in as many as one in three. Muscle aches and pains, back pain, heel pain, weakness, and slurring of speech result from statin interference with the production of Coenzyme Q₁₀ (Co-Q₁₀), needed for the muscles to function. These side effects are more common in active people, and may not show up until three years after commencement of treatment.
2. Heart Failure: Rates of heart failure have doubled since the advent of statin drugs. The heart is a muscle that depends on a plentiful supply of CO-Q₁₀.
3. Polyneuropathy: Tingling and pain in the hands and feet as well as difficulty walking occurs frequently in those taking statins, conditions often blamed on "old age" rather than on the drug.
4. Cognitive Impairment: Many patients have reported memory loss and brain fog, including total global amnesia (episodes of complete memory loss.) The implications for pilots and those driving cars and trucks are profound.
5. Cancer: In every study with rodents to date, statins have caused cancer. Most human trials are not carried out long enough to detect any increase in cancer rates, but in one trial, breast cancer rates of those taking a statin were 1500 percent higher than those of controls.
6. Depression: Numerous studies have linked low cholesterol with depression.






_{Source: Weston Price Foundation}